Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis

Peer-Reviewed Scientific Journal:
British Medical Journal

Size of study:
24 studies; 43,725 participants and 8,400 patients with cardiovascular disease (5,566 with coronary heart disease and 2,834 with cerebrovascular disease)

Summary
In a meta-analysis of twenty four studies involving 43,725 participants and 8,400 patients with cardiovascular disease (5,566 with coronary heart disease and 2,834 with cerebrovascular disease), in a comparison of the shortest versus longest third of leukocyte telomere length, the pooled relative risk for coronary heart disease was 1.54. Available observational data show an inverse association between leukocyte telomere length and risk of coronary heart disease independent of conventional vascular risk factors.

Link to study

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