Leukocyte telomere length and mortality risk in patients with type 2 diabetes

Peer-Reviewed Scientific Journal:
Oncotarget

Size of study:
568 adults with T2 diabetes

Summary
Subjects in this study were followed over a median 10.2 year time frame.  The researchers evaluated the subjects’ mortality risk factors and leukocyte telomere length was measured.  Among the study subjects that were dead or alive at follow-up, age, gender, creatinine, diabetes duration at baseline, and leukocyte telomere length were significantly different. The researchers’ analysis shows that even when adjusted for confounding factors, older age, longer disease duration and shorter telomere length significantly increased the risk of all-cause mortality for T2 diabetes patients.  The study’s authors conclude that leukocyte telomere length in combination with other clinical factors could provide prognostic value for all-cause mortality among T2 diabetes patients.

Link to study

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