Peer-Reviewed Scientific Journal:
Size of study:
143 subjects over 60 years of age
This study assessed the association between blood leukocyte average telomere length and mortality in 143 normal unrelated individuals over the age of 60 years. Individuals with shorter telomeres had poorer survival, attributable in part to a 3.18-fold higher mortality rate from heart disease (95% CI 1(.)36-7.45, p=0.0079), and an 8.54-fold higher mortality rate from infectious disease (1.52-47.9, p=0.015). These results support that telomere shortening in human beings contributes to mortality in many age-related diseases.